Are Current Dissolved CO₂ Measurement Technologies Good Enough?
As shown in Part 1 of the Dissolved CO₂ White Paper Series, dissolved CO₂ is a Critical Process Parameter (CPP) in biopharma production processes. Accurate measurement and control of DCO₂ play a key role in optimizing product quality, yield, and overall process performance.
However, the technologies commonly used today to measure and monitor dissolved CO₂ each come with fundamental limitations. These limitations can restrict real‑time process insight and reduce the effectiveness of control strategies, especially during scale‑up and long production runs.
What Does The Second Part of the DCO₂ White Paper Series Examine?
Part 2 takes a critical, technology‑focused look at the most widely used approaches for measuring dissolved CO₂ in bioprocesses. Based on Process Analytical Technology (PAT) principles, the white paper explains where each method adds value, and where it falls short when used for real‑time process monitoring and control.
Why Should You Download the Second Part, and What Will You Learn?
By downloading Part 2 of the Dissolved CO₂ White Paper Series, you will learn:
- Which dissolved CO₂ measurement technologies are commonly used in bioprocessing today
- The key limitations of indirect, off‑line, on‑line, and in‑line measurement methods
- How soft sensors, blood‑gas analyzers, off‑gas analyzers, and electrochemical sensors compare from a PAT perspective
- What measurement capabilities are required to effectively treat dissolved CO₂ as a true CPP
Download Part 2 of the Dissolved CO₂ White Paper Series
Download our white paper to gain a clear, technology‑independent assessment of current dissolved CO₂ measurement methods, so you can make informed decisions for process monitoring and control in biopharma production.