What do I need to consider when using a 34 gauge needle?

A 34 gauge needle is significantly smaller than a 33 gauge needle. For some applications the smaller size is a real advantage but has inherent complications. 34 gauge tubing requires special cutting tools to ensure the tubing is not crimped shut. Due to this limitation the needles are only available in restricted lengths and point styles. The small inner diameter (ID) results in a needle more prone to clogging, and cleaning wires are not available for this size. The small ID also makes it difficult to aspirate water with a fitted Microliter syringe; therefore, a Gastight syringe must be used with a 34 gauge needle.