Exome sequencing is becoming a widely used method for analyzing mutations associated with inherited disorders. QIAGEN and Hamilton have developed an automated protocol that allows the use of both their kits – QIAseq Human Exome (QHEx) and Actionable Exomes:NextGen Sequencing Analysis Kit xHYB (xHYBa). The single-day workflow of the kits is combined with automation and rapid analysis using QIAGEN’s CLC LightSpeed module to create a fast, cost-effective workflow.