Powerful Solutions to Invigorate Next Generation Sequencing Methods

Accelerate sequencing with less time on tedious manual library preparation and more time on data analysis. Hamilton automated liquid handling workstations fully automate library preparation workflow steps during next-generation sequencing (NGS) applications.

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Common NGS Kits and Available Hamilton Methods

  • Targeted Enrichment

    Are you tired of laborious and inefficient genetic sequencing methods? Say hello to targeted enrichment! This revolutionary technique allows for specific regions of DNA to be isolated and enriched, resulting in more accurate and reliable sequencing data. Our targeted enrichment methods utilize cutting-edge technology to provide you with high-quality results, saving you time, money, and resources. Say goodbye to traditional shotgun sequencing and hello to targeted enrichment - the future of genetic analysis.

    Check out some of the targeted enrichment methods we offer:

    Legend:

    X = Method qualified and developed in cooperation with vendor
    X = Method verified by Hamilton and/or internationally renowned customers
    X
    = Method available
    * = System configuration available up until May 2023
    ** = NGS STAR upgrades available from March 2023 onwards

    Targeted EnrichmentNGS STARletNGS STARNGS STAR 96 *NGS STAR MOA **NGS STAR V

    Agilent SureSelect XT HS2 (DNA and RNA System)

    X

    Agilent SureSelect XT Low Input Dual Index

    X

    AmpliSeq for Illumina Cancer Hotspot Panel v2

    X

    AmpliSeq for Illumina Comprehensive Panel v3

    X

    AmpliSeq for Illumina Focus Panel

    X

    IDT xGen Enrichment for Illumina (Exome Research Panel)

    X

    Illumina AmpliSeq Custom Panels

    X

    Illumina COVIDSeq

    X
    X

    Illumina DNA Prep with Enrichment

    X
    X

    Illumina DNA Prep with Exome 2.5 Enrichment

    X
    X
    X
    X
    Illumina TruSeq RNA Exome
    X
    X

    Illumina TruSight Oncology 500

    X
    X
    Illumina TruSight Oncology 500 HRD
    X

    Illumina TruSight Oncology 500 HT

    X

    Illumina TruSight RNA Fusion

    X

    Illumina TruSight Tumor 170

    X
    X

    llumina 16S rRNA Seq

    X
    X

    NEBNext ARTIC SARS-CoV-2 FS Library Prep

    X
    X

    Oxford Nanopore PCR tiling (SARS-CoV-2, ARTIC protocol)

    X

    Oxford Nanopore PCR tiling of SARS-CoV-2 ('Midnight Kit' version)

    X

    Paragon Genomics CleanPlex-SARS-CoV-2-Flex-Panel

    X

    Qiagen QIAseq DIRECT SARS-CoV-2 Kit

    X
    X

    Qiagen QIAseq Multimodal Panel

    X

    Qiagen QIAseq Multimodal Panel HT

    X

    Qiagen QIAseq SARS-CoV-2 Primer Panel & Qiagen QIAseq FX DNA

    X
    Qiagen QIAseq Targeted DNA Panel (multiple panels)
    X
    Qiagen QIAseq Targeted DNA Pro Panels
    X
    X
    Qiagen GIAseq Targeted DNNA Pro Panels (very small panels)
    X
    Roche Avenio Tumor Tissue CGP Kit
    X
    X
    Roche KAPA HyperCap Workflow v3.0
    X
    Thermo Fisher Scientific AgriSeq HTS Library Kit
    X
    Twist Bioscience Human Core Exome
    X
    Twist Bioscience SARS-CoV-2 Research Panel
    X
    X
    Twist Bioscience Exome 2.0 Library Prep with Target Enrichment
    X
  • Whole Genome Sequencing

    Are you searching for a way to gain a complete understanding of an organism's genetic blueprint? Look no further than whole genome sequencing! Our cutting-edge technology and methodologies make it possible to sequence an organism's complete genome, providing a wealth of detailed genetic information.
    Our team of experts will work with you to customize the sequencing process to meet your unique research goals, from sample preparation to data analysis. We utilize a variety of methods to ensure the highest quality results, including:

    Legend:
    X = Method qualified and developed in cooperation with vendor
    X = Method verified by Hamilton and/or internationally renowned customers
    X
    = Method available
    * = System configuration available up until May 2023
    ** = NGS STAR upgrades available from March 2023 onwards

    Whole Genome Sequencing

    NGS STARletNGS STARNGS STAR 96 *NGS STAR MOA **NGS STAR V

    Illumina DNA PCR-Free Library Prep, Tagmentation

    X
    X
    X

    Illumina DNA Prep

    X
    X

    Illumina Nextera XT

    X
    X

    Illumina TruSeq DNA PCR-Free

    X

    Illumina TruSeq Nano DNA

    X

    NEBNext Enzymatic Methyl-Seq

    X

    NEBNext Ultra II DNA Library Prep

    X
    X
    NEBNext Ultra II FS DNA Library Prep
    X

    Oxford Nanopore Genomic DNA by Ligation (SQK-LSK109-XL)

    X

    Oxford Nanopore Genomic DNA by Ligation (SQK-LSK114-XL)

    X
    X

    Oxford Nanopore Genomics Multiplex Ligation Sequencing
    (SQK-MLK111.96-XL)

    X
    PacBio Whole Genome and Metagenome Libraries using SMRTbell prep kit 3.0
    X
    X
    X
    PacBio HiFi prep Kit 96
    X
    PacBio HiFi plex prep Kit 96
    X
    Qiagen QIAseq FX DNA Library Prep
    X
    X
    X
    Revvity NEXTFLEX Cell Free DNA-Seq Library Prep Kit 2.0
    X
    Roche KAPA EvoPlus
    X
    Roche KAPA HyperPlus
    X
    X
    Roche KAPA HyperPrep
    X
    X
    Twist Bioscience Library Preparation EF 2.0 with Enzymatic Fragmentation
    and Twist Universal Adapter System
    X
  • Transcriptome Sequencing

    Want to dive deeper into the genetic makeup of your samples? Transcriptome sequencing is the key! This advanced technique allows you to sequence and analyze the complete set of RNA transcripts in your samples, providing invaluable insight into gene expression and regulation.

    Our state-of-the-art transcriptome sequencing services utilize cutting-edge technology to provide you with accurate and reliable data. We offer a range of methods to meet your specific research needs, including:

    Legend:
    X = Method qualified and developed in cooperation with vendor
    X = Method verified by Hamilton and/or internationally renowned customers
    X
    = Method available
    * = System configuration available up until May 2023
    ** = NGS STAR upgrades available from March 2023 onwards

    Transcriptome Sequencing

    NGS STARletNGS STARNGS STAR 96 *

    NGS STAR MOA **

    NGS STAR V

    Illumina Stranded mRNA Prep and Ligation

    X
    X

    Illumina Stranded Total RNA Prep Ligation with Ribo-Zero Plus

    X

    Illumina TruSeq Stranded mRNA

    X

    Illumina TruSeq Stranded Total RNA

    X

    Lexogen QuantSeq 3´mRNA-Seq Library for Illumina

    X

    NEBNext Ultra II Directional RNA (Poly(A) mRNA isolation)

    X

    NEBNext Ultra II Directional RNA (rRNA depletion)

    X

    Roche KAPA mRNA HyperPrep

    X
    X

    Roche KAPA RNA HyperPrep

    X

    Roche KAPA RNA HyperPrep Kit with RiboErase (HMR)

    X
    Takara SMART-Seq HT
    X


    Our team of experts will work with you to customize the sequencing process and provide you with high-quality data and comprehensive analysis. With our transcriptome sequencing services, you can unlock a wealth of information about gene expression and regulation, leading to new insights into disease mechanisms and potential therapeutic targets.

    Contact us today to learn more about our transcriptome sequencing services and how we can help you advance your research goals.

Advantages of Automating With Hamilton

Massive Time Efficiencies with Hamilton Automated Solutions

  • Increase sample throughput
  • Focus on high value activities through hands-free, hassle-free workflows
  • Eliminate the risk of manual errors and variation
Hamilton utilizes barcode readers to find and identify components on deck

Positively Impact Results with Hamilton Automated Solutions

  • Easily track samples and reagents via automated barcode scanning
  • Standardize workflows for consistency and reliability without user bias
  • Superior measurement accuracy, precision, and reproducibility via air displacement pipetting using Hamilton tips with CO-RE (Compressed O-Ring Expansion) technology
  • Performance monitoring, even of the most challenging liquids, through Anti-Droplet Control (ADC), Liquid Level Detection (LLD), Total Aspiration and Dispense Monitoring (TADM)

Leverage Top Tier Support with Hamilton Automated Solutions

  • Adapt to changing lab needs through scalable, modular automated solutions
  • Reduce internal validation requirements through pre-configured workflows that are qualified to work with industry-leading NGS chemistry providers
  • Receive personalized recommendations and training from dedicated Hamilton NGS experts

Solutions for Your Science

Explore the many ways in which Hamilton automated workflows benefit NGS applications.

  • Illumina Solutions
  • New England Biolabs
  • Roche-KAPA
  • PacBio Solutions
  • Library Validation and Normalization and Pooling
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Hamilton steht für Kundenservice

Egal, ob Sie ein neues Gerät oder Unterstützung für ein bereits im Labor eingesetztes Gerät benötigen: Hamilton unterstützt Sie jederzeit gerne. Unsere engagierten Mitarbeiter freuen sich auf Ihre Anfrage.

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