PE 20 tubing is compatible with Hamilton 27 gauge needles. The standard syringe that is used when connecting to PE tubing is the Hamilton Removable Needle (RN) termination. The syringe size is selected based on the injection volume of the application. Standard 27 gauge needles have a 2 inch length with a blunt needle point (point style 3). These needles are sold in convenient six-packs. The needle will connect directly to the syringe and the PE 20 tubing will fit snugly over the 27 gauge, blunt needle.