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Askion C-line Systems

Askion HS200

Automated Cryogenic Sample Storage

Automated biobanking for sample storage below -150°C

*Sold only in the United States

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The Askion C-line Systems are cryogenic storage systems for semi- or fully automated sample storage and cryopreservation. The systems can store cells, stem cells and biological samples in tubes, vials, straws and blood bags.

Features and Benefits: 

  • Modular Expandability—The systems can be expanded and integrated to create high-capacity biobanks
  • Uninterrupted Cooling Chain—Temperature stability reduces temperature oscillations during sample storage and retrieval
  • Sample Tracking—Samples are tracked from introduction through retrieval to ensure temperature stability
  • Flexible Storage—A variety of sample formats can be stored in one module
  • Ice-Free—The cryogenic working area is integrated with a dry and ice-free nitrogen atmosphere, and samples are stored and handled in the vapor phase of LN2
  • GMP Compliance

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More information can be viewed on the Askion website.

View All Hamilton Storage Product Videos

 HS200 M & L: -150°C Automated Storage 
High-capacity semi- or fully automated storage and retrieval
  • Sample handling at -130°C
  • Store different sample formats in one storage module
  • Automated single tube and SBS rack handling in one storage module
  • Store 290,000 samples in the HS200 M and 830,000 in the HS200 L
Askion HS200 L Cryogenic Storage 

HS200 S: -150°C Automated Storage

Semi- or fully automated storage and retrieval
  • Store cells, stem cells and biological samples in tubes, vials, straws and blood bags
  • Tube picking at -100°C
  • Cryogenic working area that includes an access tower and operator ports with heated gloves
  • Manual I/O lock station to maintain an ice-free system
  • Store 62,000 tubes or 84,000 straws


HS200A: Extended Storage and Retrieval

Fully automated storage and retrieval
  • Integrate multiple HS200 S stores to create one biobank
  • Pick-and-place sample processing to automatically pick samples in the cryogenic working area (below -100°C)
  • Integrated barcode scanner and vial grip adapts to the sample format
  • Temperature stability reduces temperature oscillations during sample storage and retrieval

 Askion HS200A for fully automated cryogenic storage and retrieval

WB220: -150°C Controlled-Rate Freezing

Cryogenic working area with freezer
  • Allows for up to three freezers running independently of each other
  • Provides reproducible freezing (0.01-50° C/min), programmable freezing curves and control of the seeding process
  • Cryogenic  (below -110°C) working area integrated with dry and ice-free nitrogen atmosphere
  • Maintains cold chain for shipping
  • Integrate with storage systems or use on its own

Askion WB200 cryogenic working area with freezer

HS200S* Technical Specifications
*Please contact Hamilton for HS200 M & L technical specifications



Working Room Temperature
  Ambient down to -110°C
Freezer Room Temperature
125 cm x 180 cm x 245 cm (49.2 in x 70.9 in x 96.5 in)
Weight   Full: 840 kg (1851 lbs)
Barcode reader   Integrated
Storage of Samples

LN2 Vapor Phase ≤-150°C

WB220 Technical Specifications



Working Room Temperature
  Ambient down to -110°C
Freezer Room Temperature
  +15°C down to -160°C
192 cm x 97 cm x 215 cm ± 15 cm / (75.6 in x 38.9 in x 84.6 in ± 5.9 in)
Weight   Empty: 300 kg (661.3 lbs)
 Full: 450 kg (992 lbs)
Barcode Reader   Internal 1D/2D (optional)



Learn More About Automated Cryogenic Storage

Get more information on automated cryopreservation—click on the button below to download white papers on the following topics:

  • Specimen Quality Enhancement
  • Long-Term Storage of DNA
  • Long-Term Storage of Liquid Biospecimens
  • Maximum Storage Temperatures

Download White Papers

Hamilton BiOS, Askion C-line and Microlab STAR featured in Inselspital Bern Biobank Video

© 2016 Insel Gruppe AG. Produktion: Digitale Massarbeit. Republished with permission.

Translation of the video:

(00:07) A blood sample is being stored at the Biobank of the Inselspital ("island hospital") Bern, at -150°C.

(00:15) Only one hour has passed by since the blood has been drawn, but in this time, it has gone through a whole process, which worldwide is a unique process involving efficiency and degree of automation.

(00:38) But one after the other: First, before taking the blood, the wristband of the patient is scanned. With this, the uninterrupted documentation of the sample starts.

(01:03) The sample is picked up by a courier service shortly after drawing the blood. The courier had been triggered automatically with the scan of the patient's wristband.

(01:12) The courier brings the blood sample to the Center for Laboratory Medicine of the Inselspital.

(01:21) There, the sample is centrifuged on a high-tech lab street. This does not only process samples from the biobank, but also thousands of samples which are produced through the daily operation of the Inselspital.

(01:34) The samples for the Biobank are automatically recognized, processed and transferred.

(01:50) Now the sample is split. The pipetting robot which performs this was specially developed and produced on requirements of the Biobank of the Inselspital. It distributes serum, plasma and buffy coat into tubes, which are compatible with storage down to -196°C.

(02:19) The next step: The samples are frozen down to -140°C. This happens in accordance with a predefined temperature profile. By doing it this way, the composition of large ice crystals is avoided, which ensures the highest possible quality of samples. 

(02:40) From now on, the cold chain will never be interrupted until storage. In an insulated, liquid nitrogen-filled dewar, the samples are transferred to the Biobank and put into storage there. For this purpose, two systems are available. In these tanks with liquid nitrogen, tubes are maintained at -150°C or below. On this basis, samples will fulfill highest requirements even after many years. The storage system is fully automated. The tanks have a combined capacity of 100'000 samples.

(03:16) As a second alternative, samples can be stored at -80°C in another fully automated cold storage system, which can store and administrate up to 2 million samples. The system offers triple security, does now allow ice buildup on the samples, and completely documents the samples. Only one hour after blood has been taken from the patient, the samples are stored in a way that they will be available with the highest quality to researchers for decades.