Single-Use Sensors for pH and Dissolved Oxygen
Total Process Control
When it comes to process control in the biopharmaceutical industry, engineers around the globe rely on Hamilton’s longtime expertise to deliver the highest quality process sensors. With our new breed of sensors specifically designed for single-use applications, you can now expect the same precise and hassle-free measurements in your single-use processes.
Our single-use sensors combine the reliability and measurement stability of our long-term proven conventional sensors with the ease of use as an integral part of the bioreactor. The sensors retain the high accuracy performance even after gamma irradiation and a sufficient shelf life making it the ideal single-use solution.
Ready to Use
Wide-Range Connectivity
Short Wet-In Time
Very Low Drift
Single-Use OneFerm pH Sensors
Hamilton's solution for pH measurement in a single-use process
| Criteria | Description |
|---|---|
| Gamma-sterilizable | Up to 45 kGy |
| Shaft length options | 70 mm, 120 mm, 225 mm, 325 mm, 425 mm |
| pH measuring range | 3 – 10 |
| Cytotoxicity | Non-cytoxic according to ISO 10993-5 and USP <87> after gamma sterilization |
| Shift | No shift of calibration values after gamma sterilization |
| Calibration | Calibration coefficients for manual input |
| Dry storage | Up to 18 months |
| Drift | < 0.1 pH /week |
The glass pH electrode is widely considered the most robust and reliable device available for pH measurement. Yet, traditional glass sensors are not designed for a single-use environment because they require laborious handling and increased risk of contamination.
While optical technology exists for single-use pH measurement, that technology has not delivered the reliable accuracy that bio-process engineers depend on.
By contrast, Hamilton's single-use OneFerm pH sensors feature the high-accuracy and performance of a traditional glass pH electrode, even after gamma irradiation and dry storage.
Single-Use VisiFerm DO Sensors
Hamilton's solution for dissolved oxygen measurement in a single-use process
| Criteria | Description |
|---|---|
| Gamma-irradiatable | Up to 50 kGy |
| Response time t98% | < 30s at 25°C |
| Pressure range (bar g) | 0 to 2 bar |
| Drift at room temperature | < 1% per week |
| Wetted parts | Cycloaliphatic polyamide (FDA approved, USP class VI), Silicone (FDA approved, USP class VI) |
| Wet-in time | < 30 minutes |
Hamilton's popular VisiFerm optical dissolved oxygen sensor is now available in a single-use format. Offering the same reliable electrochemical signal as a traditional sensor, the single-use version of the VisiFerm works with Hamilton's S0 and H20 cap kits and mounted directly into the bag or SU bioreactor.