Dencytee Arc Quick Checklist
The quick guide provides a walkthrough of the basic functions of your Dencytee Arc sensor.
Dencytee Arc Measurement Units
Dencytee Arc monitors in-line optical density (OD) in a wide range of processes. The total biomass sensor detects both live and dead cells, along with any debris or particulates which block light.
Dencytee Arc Total Cell Density Measurement Principle
Optical density (OD, sometimes called turbidity) is commonly used to estimate the total biomass or concentration of cells within a suspension. Cell concentrations are important to monitor in fermentation processes to detect and correct for process deviations.
Cell Density Measurement Guidelines
Process Analytical Technology (PAT) is crucial in any biopharma application. One Key Process Indicator critical to PAT implementation is how many cells are present (also known as cell density).
Wiring for Dencytee Arc Total Cell Density Sensors
Dencytee Arc total biomass sensors come standard with Modbus RTU (RS485) digital protocol. This article helps you wire a total cell density sensor.
Dencytee Arc Verification and Service Calibration
Hamilton’s intelligent in-line sensors are designed to record and transmit diagnostic data, including verification information. The verification ensures that a sensor is functioning properly.
Offline Correlations for Dencytee Arc
To use Dencytee Arc as an in-line total cell density probe, a relationship between the raw measurement signal (optical density) and the offline total cell density measurement must be established. This article will guide you through the process.
Dencytee Arc Installation
Dencytee Arc installation instructions in a bioreactor. For first time sensor use, check functionality prior to insertion into the bioreactor.
Incyte Arc PCS Connections for Existing Cell Density Users
This article reviews changes in the sensors connection strategy between the older pre-amp version of Incyte Cell Density products and the newer Incyte Arc products.
Wiring for Incyte Arc Cell Density Sensors
There are several wiring options for Incyte Arc sensors depending on the intended goals of the installation. This Knowledge Base article provides a quick guide to wiring this product for each scenario.
Data Logging Options for Incyte Arc Cell Density Sensors
There are two options to capture data with Incyte Arc Cell Density Sensors. This article provides step-by-step instructions on each.
Predicting Actionable Timeframes in Cell Culture Using In-line Cell Density Measurement
The following case study describes how in-line permittivity was utilized in a viral expression animal culture to estimate VCD in-situ and identify optimal time for viral infection using a continuous predictive model.
Incyte Cell Density Measurement Principles
Incyte enables the dual frequency measurement mode, or a frequency scanning. Learn about how Hamilton Incyte cell density sensors can continuously measure viable cells.
Dencytee (Pre-Amp) Total Cell Density Measurement Principle
Learn about how Hamilton Dencytee total cell density sensors can continuously measure viable cells.
Connecting Cell Density (Pre-amp Versions) to External Systems
This article discusses the various options to output cell density measurement data to external devices such as PLCs and control systems.
Data Analysis Tools (Cell Density Pre-Amp versions)
Hamilton provides several tools to interpret cell density data and correlate it with offline measurements. Download them here.
Incyte Sensors (Pre-amp Version) - Standard vs. Low Conductivity
There are several different options for Incyte cell density sensors based on liquid conductivity. Learn more about sensor selection / applications.
Maintaining ArcView Controller Data Storage
Recording cell density data over time can eventually fill up the hard drive of the ArcView controller. This article details the methodology to purge the controller for optimal operation.
Sensor Initialization: ArcView Cell Density Controller and ComBox (Pre-Amp Products)
ArcView Controller and Combox products used with Incyte and Dencytee (pre-amp versions) require sensor initialization. This article tackles common questions associated with this procedure.
ArcAir Data Modeling Software
VCD Soft Sensor: Close the gap between your off-line viable cell density data points.