Cell Density Knowledge Base Articles

The quick guide provides a walkthrough of the basic functions of your Dencytee Arc sensor.

Dencytee Arc monitors in-line optical density (OD) in a wide range of processes. The total biomass sensor detects both live and dead cells, along with any debris or particulates which block light.

Optical density (OD, sometimes called turbidity) is commonly used to estimate the total biomass or concentration of cells within a suspension. Cell concentrations are important to monitor in fermentation processes to detect and correct for process deviations.

Process Analytical Technology (PAT) is crucial in any biopharma application. One Key Process Indicator critical to PAT implementation is how many cells are present (also known as cell density).

Dencytee Arc total biomass sensors come standard with Modbus RTU (RS485) digital protocol. This article helps you wire a total cell density sensor.

Hamilton’s intelligent in-line sensors are designed to record and transmit diagnostic data, including verification information. The verification ensures that a sensor is functioning properly.

To use Dencytee Arc as an in-line total cell density probe, a relationship between the raw measurement signal (optical density) and the offline total cell density measurement must be established. This article will guide you through the process.

Dencytee Arc installation instructions in a bioreactor. For first time sensor use, check functionality prior to insertion into the bioreactor.

This article reviews changes in the sensors connection strategy between the older pre-amp version of Incyte Cell Density products and the newer Incyte Arc products.

There are several wiring options for Incyte Arc sensors depending on the intended goals of the installation. This Knowledge Base article provides a quick guide to wiring this product for each scenario.

There are two options to capture data with Incyte Arc Cell Density Sensors. This article provides step-by-step instructions on each.

The following case study describes how in-line permittivity was utilized in a viral expression animal culture to estimate VCD in-situ and identify optimal time for viral infection using a continuous predictive model.

Incyte enables the dual frequency measurement mode, or a frequency scanning. Learn about how Hamilton Incyte cell density sensors can continuously measure viable cells.

Learn about how Hamilton Dencytee total cell density sensors can continuously measure viable cells.

This article discusses the various options to output cell density measurement data to external devices such as PLCs and control systems.

Hamilton provides several tools to interpret cell density data and correlate it with offline measurements. Download them here.

There are several different options for Incyte cell density sensors based on liquid conductivity. Learn more about sensor selection / applications.

Recording cell density data over time can eventually fill up the hard drive of the ArcView controller. This article details the methodology to purge the controller for optimal operation.

ArcView Controller and Combox products used with Incyte and Dencytee (pre-amp versions) require sensor initialization. This article tackles common questions associated with this procedure.

VCD Soft Sensor: Close the gap between your off-line viable cell density data points.