Hplc Guard Column Family Closeup Top Bottom Margin Trimmed Img 5481

Guard columns can provide many benefits when used upstream from an analytical, preparative, or semi-preparative column. Guard columns are typically chosen to have the same packing as the primary column. Any compounds or particulate material that would block the frits or highly adsorb to the primary column will do so on the guard column, thereby protecting and extending the lifetime of the more costly column. In addition to protective uses, guard columns can be used as sacrificial preparative components.

With some applications, guard columns can be used instead of solid-phase extraction or other matrix-removing preparative steps. In many cases, this can reduce the preparative cost per sample. The use of a guard column will protect the nvestment of an analytical, preparative, or semi-preparative column.

Resources

Hamilton's knowledge base provides a range of explanatory articles, frequently asked questions, and document downloads.
Syringe Custom Built

Work with R&D engineers to customize Hamilton parts

Hamilton's "Custom Built" program puts you directly in contact with a Hamilton R&D Engineer to discuss your application and product needs. The engineer will point you to a standard solution or propose a customized solution to meet your needs.

Talk to an engineer