PRP-X200 Columns
Hamilton PRP-X200 cation exchange HPLC columns are designed for rapid, high resolution separation of alkali and alkaline earth metals. The alkali metals and ammonium are completely resolved in less than five minutes, and the alkaline earth cations separate in under four minutes. Since the mobile phase conditions are different and unique for each of the groups of cations, interferences between these groups are eliminated.
The resolution between any two ions in the alkali metal series can be increased or decreased by changing the concentration of methanol in the mobile phase. This unique feature of the PRP-X200 mobile phase/stationary phase interaction allows the chromatographer to focus on the particular ion of interest and reduce possible
interference from other ions in the sample.
The stationary phase is a sulfonated poly (styrene-divinylbenzene), so it is stable to all concentrations of organic modifiers as well as strong acids and bases. The rigid spherical polymer phase allows operation up to 5,000 psi.
The PRP-X200 columns are designed for use in all of today’s ion chromatographic equipment. Since exchange capacity is low, background signal is low. This allows low detection limits at the highest conductivity detector settings.
Resources
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USP "L" Column Listings
Explore Hamilton’s qualifying USP “L” columns. -
Choosing Column Specifications
The sample amount needed to be purified or separated for analysis will dictate which scale of chromatography is needed. In general, the scales of chromatography are microbore, analytical, semi-preparative, and preparative. Nanoscale and microscale are smaller scale ranges but are not covered in Hamilton’s product offerings. READ MORE
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