Characterizing a potential protein lead is the key to develop it into a successful drug.
The focus of research has moved to the aggregate of proteins found in a cell, an organism or tissue at a particular point in time and under specific conditions.
In addition to identifying and characterizing these proteins in high numbers, structural investigation of proteins and their actions and reactions to one another, or with organic compounds, has become the objective of research efforts.
The main technique for protein identification and characterization is In-Gel digestion followed by MALDI mass spectrometry analysis.
Automation is required to standardize this process and increase the throughput.