HOPKINTON, Mass., (Oct. 26, 2011)
– Hamilton Storage Technologies and Robotics have delivered and successfully installed an integrated compound management system at Boehringer Ingelheim (Canada) Ltd.’s Research and Development Centre in Laval, Quebec. Over 140 scientists are involved in developing new antiviral therapeutic agents at this facility. The Hamilton system provides seamless integration of compound library storage with an automated liquid handling platform for compound dilution and delivery of samples for Biological and in vitro
The complex system integrates a Hamilton ASM active sample management system with a MICROLAB STAR liquid handling workstation equipped with eight independent channels, a CO-RE (Compressed O-Ring Expansion) 384 Probe Head and grippers. The workstation includes a plate barcode labeler and sealer, a centrifuge, a Hamilton 2-D barcode reader and a Hamilton DeCapper. Hamilton’s Rack Runner robot rapidly transfers the tube racks and plates between the liquid handling platform, assay workstations and storage. The system is also integrated with the customer’s LIMS.
Incoming compounds are registered and diluted to 384-well plates for assays, while the original tube is delivered to storage. The ASM system will provide the customer with vastly improved control over sample storage conditions to ensure sample integrity and traceability.
“This is the most complex and extensive system we have installed to date,” commented Matt Hamilton, vice president of Hamilton Storage Technologies. “We expect that it will significantly improve throughput, capacity and accuracy. Sample preparation time will be decreased and more compounds will be moved through the screening process.”