The PRP-h1 offers a unique blend of high resolution C18 separation characteristics with the durability and chemical stability of a polymer support.
Polymeric 100 Å columns for LC/MS applications, synthesized DNA, and small molecules.
- pH Stable from 1 to 13
Product Features
- Unique bonding of C18 to a polymer support Reproducibility Hamilton PRP-h1 reversed phase columns are ideal for applications that require a high degree of column-to-column and batch to batch consistency (i.e., quality assurance, clinical trials). Because of the unique polymer bonding of the C18 to the PS-DVB support, PRP-h1 columns maintain their performance characteristics longer than many C8 or C18 columns. While many column manufacturers rely on other sources for their raw silica support, Hamilton manufactures its PRP-h1 support, thus assuring a consistent supply of PRP-h1 columns.
Long Life (Excellent Durability) PRP-h1 columns are packed with a poly(styrene-divinylbenzene) material. This support is pressure stable up to 5,000 psi, and highly cross-linked to prevent shrinkage or swelling (common in other polymeric columns). Since the support is polymeric, column lifetime is longer for PRP-h1 than C4, C8 or C18 columns. Regardless of whether you use ion-pair reagents or high percentage aqueous buffers (80-100%) for your separation, PRP-h1 columns outlast silica-based columns under most conditions. PRP-h1 columns will last approximately one year, while C8 and C18 columns will last only 3-4 months.
PRP-h1 Applications#470 RP Ion-Pairing Chromatography of unprotected oligonucleotides (20 and 21mer #471 Isocratic separation of two common NSAID #473 Oligonucleotide (21mer) and failure sequences #474 Unprotected 21mer Oligonucleotid
Instructions 
Catalog
Link
Datasheets
HPLC Column Application
|
Hamilton PRP-h1, 100 Å C18 bonded to a polymeric support for oligonucleotides, NSAIDs and many other HPLC applications. 
